The Experts in Animal Health

Brakke Consulting’s
Animal Health News & Notes for February 26, 2021
Copyright © Brakke Consulting
Editor: Lynn Fondon DVM MBA


Brakke Consulting News
Pain Management Products report 

Earnings News
Apiam Animal Health

Other News
Algenex SL
American Veterinary Group
Destination Pet
Elanco (Increxxa)
Elanco (Credelio CAT)
Elanco (Credelio Plus)
Enso Discoveries
EveryCat Health Foundation
Exceptional Pets
Invatech Health
Meyenberg International Group
Mid America Pet Food
MWI Animal Health
NanoSmart Pharmaceuticals
Natural Biologics
Oak Hill Capital
Oncology Pharma
Pawzitivity Pet Products
TA Associates
Vetsina Animal Diagnostics
Winn Feline Foundation



Pain management is one of the leading topics in veterinary medicine today. Brakke Consulting’s annual report on Pain Management Products for Dogs and Cats includes such valuable information as:
– overview of acute and chronic pain in small animals

– discussion of the impact of the human opioid crisis on veterinary use of opioids
– review of new products, including performance of deracoxib generics
– estimates of US sales and prices of leading products
– pain management products in development, including monoclonal antibody products LIBRELA and SOLENSIA
– review of nutritional supplements used for chronic pain
– review of therapeutic diets for joint care
– discussion of the use of cannabinoids in veterinary pain management
– 2021 survey of 340 small animal veterinarians regarding use of pain management products

Pain Management Products for Dogs and Cats 2021 can be purchased for $5,500 if ordered by March 12, 2021, and $5,950 thereafter. The report will be completed in late March. Questions about the study can be answered by project manager Lynn Fondon, DVM, MBA at


  • Elanco Animal Health reported its financial results for the full year of 2020. Total revenue was $3,273 million, an increase of 7% over the previous year, including the addition of $592 million of Bayer Animal Health product revenue. Reported net loss was $(560.1) million compared to net income of $67.9 million in 2019. Adjusted EBITDA for the year was $528.5 million, a decline of 20% from 2019. (company press release)
  • Dechra Pharmaceuticals announced results for the first half of fiscal 2021, ended December 31. Revenues were GBP 299.8 million ($421 million), an increase of 21% year-over-year. EBITDA for the six months reached GBP 88.2 million ($124 million), an improvement of 30%. The company’s North American business grew 17% to GBP 104.2 million ($146 million). (IHS Markit Connect)
  • Heska Corporation reported financial results for the full year ended December 31, 2020. Revenues were $197 million, a year-over-year increase of 61% due in large part to the impact of the acquisitions of international companies CVM Diagnostico Veternario S.L., CVM Ecografia S.L., and scil. Net loss attributable to Heska was $(14.4) million compared to a net loss of $(1.5) million in 2019. North American revenue was $131 million, an increase of 14%. (company website)
  • Freshpet, Inc. reported financial results for its full year ended December 31, 2020. Net sales were $319 million, an increase of 30% over the prior year. Net loss was $(3.2) million compared to a net loss of $(1.4) million in 2019. (Globe Newswire)
  • ImmuCell announced the Company’s unaudited financial results for the year ended December 31, 2020. Total product sales were $15.3 million, an increase of 12% compared to the prior year. EBITDA increased to $1.89 million for the year, compared to $1.43 million during the year ended December 31, 2019. (company press release)
  • Swedencare announced financial results for the year 2020. Revenues for the year were SEK240 million ($29 million), an increase of 89% boosted by its acquisitions of Animal Pharmaceuticals and Nutravet. EBITDA for 2020 amounted to SEK70.3 million ($8.5 million), a year-on-year increase of 78%. (IHS Markit Connect)
  • Apiam Animal Health reported results for the half-year ended December 31, 2021. Revenue was A$61.2 million (US$ 47 million); underlying net profit was A$2.7 million US$ 2.1 million). (
  • BarkBox , reported results for its third fiscal quarter ended December 31, 2020. Sales increased 78% to an estimated $105 million compared to the year-ago period. New subscriptions increased 66% to 381,000. (Pet Product News)


The KC Animal Health Corridor is now accepting applications from early-stage companies to present at the 13th annual Animal Health Summit, held virtually August 24-26, 2021.

The 13th annual Summit is one of the only opportunities in the world for early-stage companies in the animal health and nutrition sectors to present their vision, business plan and technology to potential investors.

The selection committee will consider companies that meet the following criteria:
– Seeking $500,000 – $20 million in funding, or strategic partnerships to advance a company’s technology
– Revenue projections of $20 million within 5-7 years

Applications are due by April 5. To apply to present as an emerging company, visit the Animal Health Summit application page .

For more information, contact Kimberly Young at


  • Elanco announced that the FDA has approved Increxxa (generic tulathromycin injection) for the treatment of bovine respiratory disease and swine respiratory disease. (company press release)
  • Elanco announced it received the final technical section complete letters from the FDA for Credelio CAT (lotilaner), anticipated to be the first oral flea and tick treatment to be licensed for cats, with product approval expected in the second quarter. (company press release)
  • Ceva Santé Animale and INRAE announced they have signed a first framework agreement aimed at consolidating their collaboration in animal health, affirming a shared objective of conducting joint “One Health” work. The existing partnership – in addition to licensing INRAE technologies – involves many forms of collaboration, including exchange of laboratory personnel, testing of anti-infective treatments and vaccines and several joint research projects scheduled to be completed in 2021. (company press release)
  • Virbac and Algenex SL announced that they have entered into an international licensing agreement for the development and commercialization of a CrisBio-based vaccine in a major swine indication. The vaccine will be developed jointly and manufactured using CrisBio, Algenex’ proprietary and patent protected Baculovirus vector-mediated expression platform that harnesses the power of insects to act as natural single-use bioreactors. Financial terms were not disclosed. (Globenewswire)
  • Bimeda announced the launch of Macrosyn (generic tulathromycin injection), a ready-to-use injectable antibiotic for use in cattle and swine. According to the company Macrosyn is the first generic alternative to Draxxin to reach the market in the US. (company press release)
  • Hill’s Pet Nutrition announced the launch of Prescription Diet Derm Complete food. The company says it is the world’s first and only nutritional solution that is clinically proven to tackle both food and environmental sensitivities in dogs. The diet, which uses egg as its single intact animal protein, contains nutrients to help strengthen the skin’s natural barrier against environmental allergens and the Histaguard complex with bioactives and phytonutrients to help manage a dog’s response to environmental allergens. (
  • Enso Discoveries introduced Rebound PRP and PRF (platelet rich fibrin) kits for use in canine, feline, equine and bovine patients. Validated by Kansas State University’s College of Veterinary Medicine, Rebound kits have a 2-year shelf life and require just 20 minutes from draw to injection. (company announcement)
  • Oak Hill Capital announced its investment and partnership with American Veterinary Group, which partners with over 150 veterinarians across nearly 50 veterinary practices and veterinary urgent care clinics throughout the South and Southeast. Terms were not disclosed. (PRNewswire)
  • PetDesk announced the launch of a Pet Insurance Guide tool, a new way for companion animal owners to select insurance policies. The tool will be available on the PetDesk app in the US. (IHS Markit Connect)
  • TA Associates announced it has acquired Mid America Pet Food, manufacturer of Victor Super Premium Pet Food and Eagle Mountain Pet Food. Financial terms were not disclosed. (Pet Product News)
  • Vet2Pet announced the release of Curbside Arrival Alerts, and add-on service for existing Vet2Pet clients that will simplify the curbside check-in process for veterinary team members and their clients, leading to improved pet owner and team member experiences at veterinary hospitals. (
  • Vetsina Animal Diagnostics announced it is seeking up to GBP 3 million from investment partners to commercialize its microRNA-based diagnostic tests for the animal health market. Vetsina was formed last year as a joint venture between Roslin Technologies and Destina Genomics, and is initially focused on detecting microRNA biomarkers for infections, illnesses and disease in animals. It is on target to launch its first product in Q3 this year. (company press release)
  • French botanicals producer Nor-Feed announced it has established a distribution partnership with animal health company Natural Biologics to improve access to its plant extracts for existing and US customers. Nor-feed products already introduced in the US include grape extracts, saponins, and a premix based on citrus extracts. (Feednavigator)
  • Oncology Pharma, Inc. announced that it has extended a world-wide Licensing Agreement with NanoSmart Pharmaceuticals, Inc. for use in the veterinary oncology market. Nanosmart possesses proprietary technology and intellectual property rights for the development of liposomal and/or emulsion-based drug formulations that incorporate anti-nuclear antibodies (ANA). (Globenewswire)
  • iBio announced plans to gain a US Veterinary Biologics Establishment License from the USDA for its Texas facility. The company’s FastPharming plant will be the manufacturing site of its lead animal health candidate IBIO-400 – a vaccine for classical swine fever (CSF). iBio worked with Texas A&M University and Kansas State University to develop a safe and effective subunit DIVA vaccine for CSF. (IHS Markit Connect)
  • Pawzitivity Pet Products announced it has acquired com. Financial terms were not disclosed. (Pet Product News)
  • Destination Pet announced it has acquired Exceptional Pets, an Arizona-based veterinary care and boarding/grooming company with five locations. Financial terms were not disclosed. (Pet Product News)
  • Winn Feline Foundation, a feline-focused nonprofit organization with more than 50 years’ history, announced a name change to EveryCat Health Foundation to better embody a global vision for cat health and welfare. (Veterinary Practice News)
  • EU Elanco announced that the Committee for Medicinal Products for Veterinary Use (CVMP) delivered a positive opinion on the granting of a Community marketing authorization for Credelio Plus Chewable tablets for dogs (lotilaner/milbemycine oxyme). (company press release)
  • EU Zoetis announced that the European Commission has granted the marketing authorization for Solensia (frunevetmab), a once-monthly injectable feline osteoarthritis treatment to alleviate pain that targets Nerve Growth Factor (NGF) using a monoclonal antibody. (company press release)
  • UK MWI Animal Health and Invatech Health announced a new distribution service for the dispensing of animal prescriptions issued by veterinarians in the UK.  Invatech’s Patient Medication Record (PMR) system – known as Titan – was modified to support the creation of the MWI’s Home Pharmacy service. The new service will enable veterinary clinics to prescribe medication and have the product shipped directly to the owner’s home or returned to the practice.  (
  • EU Animalcare announced it has received a positive opinion for a marketing authorization from the European Medicines Agency’s (EMA) Committee for Medicinal Products for Veterinary Use (CVMP) for Daxocox (enflicoxib), a novel COX-2 inhibitor for the treatment of pain and inflammation associated with osteoarthritis or degenerative joint disease in dogs. A decision on the product’s approval is expected early in the second quarter of 2021. (IHS Markit Connect)
  • LATIN AMERICA Avivagen announced that it has chosen Meyenberg International Group to lead expansion efforts in key regions in Central and South America. Meyenberg has been critical to Avivagen’s recent success in Mexico and will begin by overseeing the process to seek registrations for OxC-beta Livestock in Costa Rica, Colombia, Peru, Uruguay and Argentina. (company press release)





  • GERMANY – ASF African swine fever in Germany’s wild boar population has surpassed 600 cases, and the agriculture minister is urging states to do whatever they can to protect the domestic pig population. The country has been dealing with ASF for nearly half a year, and while domestic swine haven’t tested positive, Germany’s pork industry has been hit: Several key export markets, including China, have closed their borders to German pig meat. (Vet Advantage)
  • US – VETERINARY INITIATIVE A large number of veterinary associations have started a new collaboration called Veterinary Visionaries to bring their collective memberships together to share ideas, co-create solutions, and unify our industry’s approach to solving shared challenges. The American Animal Hospital Association (AAHA) is joined by the American Association of Veterinary State Boards, the American College of Veterinary Internal Medicine, the American Veterinary Medical Association, and many other state and national associations in this unique initiative. In the long term, Veterinary Visionaries will build a community and programs that work toward solutions to big issues such as addressing a lack of diversity in the profession and ongoing public health concerns, as well as strategically planning for opportunities such as telehealth, including advanced technology and AI, and keeping pace with evolving veterinary science. (association press release)
  • US – SURGERY RESEARCH Researchers at the University of Arkansas have created a surgical spoon to remove bladder stones in companion animals. The tool is currently in clinical testing at local veterinary clinics.(Vet Advantage)
  • US – RESEARCH FUNDING The USDA’s Animal and Plant Health Inspection Service (APHIS) announced the awarding of $14.4 million to fund 76 projects being undertaken by states, universities and other organization to bolster programs protecting animal health.  (JAVMA)


The Association of American Veterinary Medical Colleges (AAVMC) recently released a new statement on global veterinary medical education, stating that the AAVMC supports policies that foster and protect international collaborations in veterinary education and movements of veterinary professionals and students. In light of recent challenges faced by many countries in dealing with outbreaks of African swine fever (ASF) and the COVID-19 pandemic, the AAVMC statement is very timely and should be seriously considered and implemented by all stakeholders of animal health and public health.

Currently less than 1% of veterinary students in the U.S. are foreign nationals.  In addition to encouraging more international students to apply to DVM programs in the U.S., we should also encourage more American veterinary students seek job opportunities globally. It’s in everyone’s best interest that our foreign veterinary graduates and their American classmates work together to train more qualified field veterinarians and small animal clinicians around the world.

The transboundary nature of emerging and re-emerging high-consequence zoonosis and animal infectious disease threats requires global cooperation, not only in outbreak management, but also in research and education for a broader biomedical, social, and ecological understanding of disease systems. The One Health concept will become a successful approach only when the world has sufficient and competent veterinarians.

Jishu Shi


In last week’s poll, we asked you how the weather had impacted you.  45% of you said you had to shovel snow, and 42% set a new record for cold temperature; one-third had to scrape ice. For many of us, it was a less-than-productive work week – 20% lost power and nearly that many lost internet access too. A lucky 28% of you said it was a normal week in February where you live.  Let’s hope that Mother Nature doesn’t have any more tricks up her sleeve.

This week

In keeping with the One Health theme of this week’s comments, let’s find out about the global footprint of the companies you work for.

Do you work for a company with an international presence? If so, what percentage of its revenues are generated outside the US?

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