{"id":33022,"date":"2023-12-01T08:28:37","date_gmt":"2023-12-01T14:28:37","guid":{"rendered":"https:\/\/brakkeconsulting.com\/?p=33022"},"modified":"2023-12-01T08:28:57","modified_gmt":"2023-12-01T14:28:57","slug":"brakke-consulting-viewpoint-december-1-2023","status":"publish","type":"post","link":"https:\/\/brakkeconsulting.com\/ja\/brakke-consulting-viewpoint-december-1-2023\/","title":{"rendered":"\u30d6\u30e9\u30c3\u30b1 \u30d3\u30e5\u30fc\u30dd\u30a4\u30f3\u30c8 2023 \u5e74 12 \u6708 1 \u65e5"},"content":{"rendered":"<p>\u3053\u306e\u30cb\u30e5\u30fc\u30b9\u30ec\u30bf\u30fc\u306b\u306f\u3001Loyal (\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u5dde\u30b5\u30f3\u30d5\u30e9\u30f3\u30b7\u30b9\u30b3\u306e Cellular Longevity, Inc. \u306e\u4e00\u90e8) \u304c\u958b\u767a\u4e2d\u306e\u65b0\u85ac\u306b\u95a2\u3059\u308b\u8a00\u53ca\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002Loyal \u306e\u85ac\u306f LOY-001 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(IGF-1) \u3092\u8abf\u6574\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002IGF-1 \u306f\u8001\u5316\u3068\u5bff\u547d\u306b\u95a2\u4fc2\u3057\u3001\u72ac\u3067\u306f\u4f53\u306e\u5927\u304d\u3055\u3092\u6c7a\u5b9a\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6700\u521d\u306e\u88fd\u54c1\u306f\u3001\u5c0f\u578b\u72ac\u3088\u308a\u3082\u4e00\u822c\u7684\u306b\u5bff\u547d\u304c\u77ed\u3044\u5927\u578b\u6210\u72ac\u7528\u306e\u5f90\u653e\u6027\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u3068\u3057\u3066\u63d0\u4f9b\u3055\u308c\u308b\u4e88\u5b9a\u3067\u3059\u3002Loyal 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Longevity, Inc.\u5098\u4e0b\uff09\u304c\u958b\u767a\u4e2d\u306e\u65b0\u85ac\u306b\u95a2\u3059\u308b\u60c5\u5831\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002Loyal\u793e\u306e\u85ac\u5264\uff08LOY-001\uff09\u306f\u3001\u72ac\u306e\u5bff\u547d\u3092\u5ef6\u3070\u3059\u52b9\u679c\u3092\u6301\u3064\u3068\u3057\u3066\u3001\u6700\u7d42\u7684\u306b\u627f\u8a8d\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002Loyal\u793e\u306f\u4eca\u9031\u3001\u7c73\u56fdFDA\u306b\u3088\u308b\u300c\u63d0\u4f9b\u3055\u308c\u305f\u30c7\u30fc\u30bf\u306f\u3001\u6709\u52b9\u6027\u304c\u5408\u7406\u7684\u306b\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u3092\u793a\u3059\u306e\u306b\u5341\u5206\u3067\u3042\u308b\u300d\u3068\u3044\u3046\u7d50\u8ad6\u3092\u767a\u8868\u3057\u3001\u5e83\u304f\u5831\u9053\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u7d50\u8ad6\u306f\u3001\u65e9\u3051\u308c\u30702026\u5e74\u306bFDA\u306b\u3088\u308b\u6761\u4ef6\u4ed8\u304d\u627f\u8a8d\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002LOY-001\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u6210\u9577\u56e0\u5b50-1\uff08IGF-1\uff09\u3092\u8abf\u7bc0\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002IGF-1\u306f\u8001\u5316\u3068\u5bff\u547d\u306b\u95a2\u9023\u3057\u3001\u72ac\u306b\u304a\u3044\u3066\u306f\u4f53\u683c\u3092\u6c7a\u5b9a\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6700\u521d\u306e\u88fd\u54c1\u306f\u3001\u5c0f\u578b\u72ac\u3088\u308a\u3082\u4e00\u822c\u7684\u306b\u5bff\u547d\u304c\u77ed\u3044\u5927\u578b\u6210\u72ac\u7528\u306e\u5f90\u653e\u6027\u30a4\u30f3\u30d7\u30e9\u30f3\u30c8\u3068\u3057\u3066\u63d0\u4f9b\u3055\u308c\u308b\u4e88\u5b9a\u3067\u3059\u3002Loyal\u793e\u306f\u3001\u6210\u72ac\u306e\u5bff\u547d\u3092\u5ef6\u3070\u3059\u305f\u3081\u306e\u5f8c\u7d9a\u5316\u5408\u7269\u3068\u3057\u3066\u3001\u4ed6\u306b\u3082\u3044\u304f\u3064\u304b\u306e\u88fd\u54c1\u3092\u958b\u767a\u4e2d\u3067\u3059\u3002\u7d4c\u53e3\u6295\u4e0e\u3067\u3082\u52b9\u679c\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4ed6\u306e\u4f01\u696d\u3084\u7814\u7a76\u6a5f\u95a2\u3082\u3001\u72ac\u306e\u5bff\u547d\u3092\u5ef6\u3070\u3059\u3068\u3044\u3046\u540c\u3058\u76ee\u6a19\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u3092\u767a\u8868\u3057\u3066\u3044\u307e\u3059\uff08\u3082\u3061\u308d\u3093\u3001\u3053\u308c\u306f\u4eba\u9593\u3067\u3082\u540c\u69d8\u306e\u7814\u7a76\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff09\u3002\u307e\u3060\u521d\u671f\u6bb5\u968e\u3067\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u3053\u306e\u7814\u7a76\u306f\u30da\u30c3\u30c8\u306e\u5065\u5eb7\uff08\u305d\u3057\u3066\u5bff\u547d\uff09\u306b\u3001\u3072\u3044\u3066\u306f\u7363\u533b\u5b66\u306e\u5b9f\u8df5\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4eca\u5f8c\u306e\u52d5\u5411\u306b\u6ce8\u76ee\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n<div class=\"view-full-post\"><a href=\"https:\/\/brakkeconsulting.com\/ja\/brakke-consulting-viewpoint-december-1-2023\/\" class=\"view-full-post-btn\">\u5168\u6587\u3092\u898b\u308b<\/a><\/div>\n<p>;<\/p>","protected":false},"author":19,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[43],"tags":[],"class_list":["post-33022","post","type-post","status-publish","format-standard","hentry","category-viewpoints"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>News from Brakke Consulting<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/brakkeconsulting.com\/ja\/brakke-consulting-viewpoint-december-1-2023\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"News from Brakke Consulting\" \/>\n<meta property=\"og:description\" content=\"This newsletter contains a reference to a new drug in development by Loyal (part of Cellular Longevity, Inc. of San Francisco, CA.).\u00a0 Loyal\u2019s drug, identified only as LOY-001, may eventually be approved to provide life extension in dogs.\u00a0 This week, Loyal released a widely reported conclusion by the US FDA that \u201cthe data you provided are sufficient to show that there is a reasonable expectation of effectiveness,\u201c which could lead to conditional approval by FDA as early as 2026. LOY-001 is thought to modulate insulin growth factor-1, or IGF-1, which is associated with aging and longevity, and in dogs is known to play a role in determining body size.\u00a0 This initial offering is expected to be available as an extended release implant for use in large adult dogs, which generally have shorter lifespans than small dogs.\u00a0 Several other products are also in Loyal\u2019s pipeline as follow-on compounds to also provide extended life in adult dogs, and may be effective in oral form as well.\u00a0 Other companies and research institutions have also announced other projects focused on this same goal of extending lifespans in dogs (which of course could lead to similar work in humans). While in its infancy, this work could profoundly affect the health (and the lifespans) of pets and therefore the practice of veterinary medicine.\u00a0 We\u2019ll keep anView Full Post;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/brakkeconsulting.com\/ja\/brakke-consulting-viewpoint-december-1-2023\/\" \/>\n<meta property=\"og:site_name\" content=\"Brakke Consulting Website\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-01T14:28:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-12-01T14:28:57+00:00\" \/>\n<meta name=\"author\" content=\"Amanda McDavid\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u57f7\u7b46\u8005\" \/>\n\t<meta name=\"twitter:data1\" content=\"Amanda McDavid\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/\"},\"author\":{\"name\":\"Amanda McDavid\",\"@id\":\"https:\/\/brakkeconsulting.com\/#\/schema\/person\/cbd3330707aa1f20925a2f9d78722615\"},\"headline\":\"Brakke Viewpoint December 1, 2023\",\"datePublished\":\"2023-12-01T14:28:37+00:00\",\"dateModified\":\"2023-12-01T14:28:57+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/\"},\"wordCount\":258,\"articleSection\":[\"Viewpoints\"],\"inLanguage\":\"ja\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/\",\"url\":\"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/\",\"name\":\"News from Brakke Consulting\",\"isPartOf\":{\"@id\":\"https:\/\/brakkeconsulting.com\/#website\"},\"datePublished\":\"2023-12-01T14:28:37+00:00\",\"dateModified\":\"2023-12-01T14:28:57+00:00\",\"author\":{\"@id\":\"https:\/\/brakkeconsulting.com\/#\/schema\/person\/cbd3330707aa1f20925a2f9d78722615\"},\"breadcrumb\":{\"@id\":\"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/#breadcrumb\"},\"inLanguage\":\"ja\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/brakkeconsulting.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Brakke Viewpoint December 1, 2023\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/brakkeconsulting.com\/#website\",\"url\":\"https:\/\/brakkeconsulting.com\/\",\"name\":\"Brakke Consulting Website\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/brakkeconsulting.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"ja\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/brakkeconsulting.com\/#\/schema\/person\/cbd3330707aa1f20925a2f9d78722615\",\"name\":\"Amanda McDavid\",\"url\":\"https:\/\/brakkeconsulting.com\/ja\/author\/amanda\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Brakke Consulting\u304b\u3089\u306e\u30cb\u30e5\u30fc\u30b9","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/brakkeconsulting.com\/ja\/brakke-consulting-viewpoint-december-1-2023\/","og_locale":"ja_JP","og_type":"article","og_title":"News from Brakke Consulting","og_description":"This newsletter contains a reference to a new drug in development by Loyal (part of Cellular Longevity, Inc. of San Francisco, CA.).\u00a0 Loyal\u2019s drug, identified only as LOY-001, may eventually be approved to provide life extension in dogs.\u00a0 This week, Loyal released a widely reported conclusion by the US FDA that \u201cthe data you provided are sufficient to show that there is a reasonable expectation of effectiveness,\u201c which could lead to conditional approval by FDA as early as 2026. LOY-001 is thought to modulate insulin growth factor-1, or IGF-1, which is associated with aging and longevity, and in dogs is known to play a role in determining body size.\u00a0 This initial offering is expected to be available as an extended release implant for use in large adult dogs, which generally have shorter lifespans than small dogs.\u00a0 Several other products are also in Loyal\u2019s pipeline as follow-on compounds to also provide extended life in adult dogs, and may be effective in oral form as well.\u00a0 Other companies and research institutions have also announced other projects focused on this same goal of extending lifespans in dogs (which of course could lead to similar work in humans). While in its infancy, this work could profoundly affect the health (and the lifespans) of pets and therefore the practice of veterinary medicine.\u00a0 We\u2019ll keep anView Full Post;","og_url":"https:\/\/brakkeconsulting.com\/ja\/brakke-consulting-viewpoint-december-1-2023\/","og_site_name":"Brakke Consulting Website","article_published_time":"2023-12-01T14:28:37+00:00","article_modified_time":"2023-12-01T14:28:57+00:00","author":"Amanda McDavid","twitter_card":"summary_large_image","twitter_misc":{"\u57f7\u7b46\u8005":"Amanda McDavid","\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593":"2\u5206"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/#article","isPartOf":{"@id":"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/"},"author":{"name":"Amanda McDavid","@id":"https:\/\/brakkeconsulting.com\/#\/schema\/person\/cbd3330707aa1f20925a2f9d78722615"},"headline":"Brakke Viewpoint December 1, 2023","datePublished":"2023-12-01T14:28:37+00:00","dateModified":"2023-12-01T14:28:57+00:00","mainEntityOfPage":{"@id":"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/"},"wordCount":258,"articleSection":["Viewpoints"],"inLanguage":"ja"},{"@type":"WebPage","@id":"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/","url":"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/","name":"Brakke Consulting\u304b\u3089\u306e\u30cb\u30e5\u30fc\u30b9","isPartOf":{"@id":"https:\/\/brakkeconsulting.com\/#website"},"datePublished":"2023-12-01T14:28:37+00:00","dateModified":"2023-12-01T14:28:57+00:00","author":{"@id":"https:\/\/brakkeconsulting.com\/#\/schema\/person\/cbd3330707aa1f20925a2f9d78722615"},"breadcrumb":{"@id":"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/#breadcrumb"},"inLanguage":"ja","potentialAction":[{"@type":"ReadAction","target":["https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/brakkeconsulting.com\/brakke-consulting-viewpoint-december-1-2023\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/brakkeconsulting.com\/"},{"@type":"ListItem","position":2,"name":"Brakke Viewpoint December 1, 2023"}]},{"@type":"WebSite","@id":"https:\/\/brakkeconsulting.com\/#website","url":"https:\/\/brakkeconsulting.com\/","name":"Brakke Consulting\u306e\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/brakkeconsulting.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"ja"},{"@type":"Person","@id":"https:\/\/brakkeconsulting.com\/#\/schema\/person\/cbd3330707aa1f20925a2f9d78722615","name":"\u30a2\u30de\u30f3\u30c0\u30fb\u30de\u30af\u30c7\u30a4\u30d3\u30c3\u30c9","url":"https:\/\/brakkeconsulting.com\/ja\/author\/amanda\/"}]}},"_links":{"self":[{"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/posts\/33022","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/comments?post=33022"}],"version-history":[{"count":2,"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/posts\/33022\/revisions"}],"predecessor-version":[{"id":33025,"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/posts\/33022\/revisions\/33025"}],"wp:attachment":[{"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/media?parent=33022"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/categories?post=33022"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/brakkeconsulting.com\/ja\/wp-json\/wp\/v2\/tags?post=33022"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}